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Proven To Drive Sustained Weight Loss and Improved Metabolic Health At Scale

Backed by three years of data, Calibrate’s Metabolic Reset program demonstrates sustained, clinically significant results, showcasing its long-term effectiveness and impact on members' health. With a cohort size of over 17,000 members, our largest to date, our Metabolic Reset program delivers robust insights and proven results across a diverse group of participants.

Four Years In Since Our Earliest Members Joined, Our Data Is Clear: Calibrate Works

Unlike 95% of diets that fail, our members sustained 16% average weight loss at 12 months, 17% at 24 months, and 19% at 36 months. Our comprehensive program has also helped thousands of members make significant improvements to their metabolic health, including improving every metabolic marker, from blood glucose and inflammation to heart and liver disease risk.

19% Average Weight Loss Achieved over 3 years

Calibrate's results prove our proprietary program is effective at driving long-term improvements to metabolic health and weight loss.

  • Calibrate demonstrates an average of 15% weight loss at 12 months, 17.2% at 24 months, and 19.1% at 36 months. Calibrate members have also decreased their waist circumference by 6.1 inches, on average.

80% of members say Calibrate is more effective than other programs

Our data isn’t from a clinical trial. Behind Calibrate’s results are thousands of members like you, with ups and downs, setbacks and comebacks. 80% of members say Calibrate is more effective than other programs. By working with members for a year or more, Calibrate focuses on creating lasting change, turning small wins into big wins over time.

Calibrate Member, Donya, at 12 months

With Calibrate, Members Make Demonstrable Improvements to Their Metabolic Health

Our combination of medication and lifestyle intervention drives significant improvements in metabolic health.

  • 83% of members showed improvement in hs-CRP, a key measure of inflammation
  • 81% of members improved their hemoglobin A1c
  • 76% of members who started the program with diabetes or prediabetes achieved normal HbA1c levels by program completion
  • 73% of members reduced their triglycerides

The Bottom Line: Calibrate Works, Guaranteed

Calibrate stands behind its results—so much so that our Results Money-Back Promise commits to achieving at least 10% weight loss for members who stay 12 consecutive months on our program. We guarantee at least 10% because research shows that 10% body weight loss meaningfully improves health outcomes and is sustainable. We’re proud to be the only program to make this commitment based on our track record of success.

With each member we serve, Calibrate gets closer to achieving our mission to change the way the world treats weight.

Backed by science   •   Backed by science   •   

Methodology

The results report analysis includes data from several Calibrate member cohorts. For full population weight outcomes, we evaluated 21,214 individuals who had received at least one month of a GLP-1 medication and completed at least 12 months of the Metabolic Reset, 17,475 of whom had a valid 12-month weight, as well as smaller subsets from this group who continued in the program and had valid weights at 24 months (n=5,137) and 36 months (n=442). This cohort included a subset of enterprise members who had reached 12 months in the program (n=150) and had weights at that time point (n=145). This expanded dataset represents our largest cohort to date and provides unprecedented insight into the long-term effectiveness of our comprehensive approach to obesity treatment. The data for metabolic markers, patient-reported outcomes for health habits, program satisfaction, and member engagement come from members in this cohort who completed specific metabolic lab tests or surveys (with the relevant n’s provided for each set of metrics). For additional cohort information or more details about our methodology see the full report.