How is GLP-1 medication different from phentermine?

Phentermine is a molecule made from amphetamine that’s used to treat obesity. It's a controlled substance that promotes weight loss by suppressing appetite. Because phentermine is a stimulant, it has several known neurological, gastrointestinal, and cardiovascular side effects. Importantly, it can cause a significant elevation in blood pressure—which can force your heart to work harder and exacerbate any existing heart conditions.

The GLP-1 medications used in the Calibrate program, on the other hand, are not stimulants. Rather, they are analogous to hormones naturally made by your body and they work directly on the aspects of your biology that are critical for metabolic health and weight.